FERTILITY FACTS, NEWS AND VIEWS –Letrozole May Help Women diagnosed with Polycystic Ovarian Syndrome Conceive

PCOS affects 5 to 10% of women of childbearing age resulting in problems conceiving. PCOS is one of the leading causes of infertility, with symptoms of  absent of  ovulation, resulting in very irregular are absent periods, weight problems, facial hair and thinning hair on scalp.

A recent article published in Science Daily, reports that a nationwide study led by Penn State College of Medicine researchers, found that the drug Letrozole, results in higher birth rate for women diagnosed with PCOS, over the conventional treatment, Clomiphene Citrate, (a drug that stimulates ovulation), which results in only 22% success rate with up to six cycles of treatment.

The study also found that fewer twin pregnancies were associated with the drug Letrozole, 3.9%, compared to 6.9% on Clomiphene Citrate.

Read more by following the link below:-

http://www.sciencedaily.com/releases/2014/07/140709182159.htm

The more we know.........

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OBESITY AND INFERTILITY

Obesity is widely known to be a cause of infertility and is also a common symptom of Polycystic Ovarian Syndrome (PCOS).

How exactly does obesity interfere with your efforts to conceive? Findings from a recent study done by researchers from Antwerp, Hull, and Madrid, are that eggs exposed to high levels of saturated fatty acids, found in the ovaries of obese women, interferes with the development of the embryo.

The study found that embryos developed from cattle with high levels of saturated fatty acids, had fewer cells, altered gene expression and altered metabolic activity, all indicative of reduced egg viability.

Although this study was done on cows, it could help to explain why obese women and women with diabetes, have problems conceiving.

Read more by following the link below:-

http://www.medicalnewstoday.com/releases/232941.php

From the article

"The most viable embryos, those most likely to result in a successful pregnancy, have a 'quieter', less active metabolism, particularly in relation to amino acids," explains Dr Sturmey. "Where eggs were exposed to high levels of fatty acids, the resulting embryos showed increased amino acid metabolism and altered consumption of oxygen, glucose and lactate - all of which indicates impaired metabolic regulation and reduced viability." 

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